首页
登录
职称英语
British doctors are to launch a major clinical trial to investigate whether
British doctors are to launch a major clinical trial to investigate whether
游客
2023-08-14
22
管理
问题
British doctors are to launch a major clinical trial to investigate whether a common anti-depression drug could be a cheap and effective treatment for the destructive condition motor neurone(运动神经元)disease.
The trial, which is due to start in January, will follow more than 200 patients with motor neurone disease over 18 months to see if those given daily lithium pills live longer. Lithium is already licensed for treating depression and other mental disorders, and is extremely cheap, costing just 48p for a packet of 20 pills.
The £1m trial follows the publication in February of a small study by Italian researchers which suggested that lithium could slow the progression of the disease dramatically. The study sparked a surge of interest in the drug among online patient groups, and some doctors now offer lithium "off-label", despite widespread uncertainty as to whether it works.
Nigel Leigh, director of the motor neurone disease care centre at King’s College London, who will lead the trial, said: "It is our responsibility and duty to carry out this trial because we have to consider every lead seriously, and where there is real uncertainty, resolve it swiftly. The results of the Italian trial are too dramatic to ignore."
Motor neurone disease destroys nerves in the brain that control movement, leaving patients locked in a failing body. There is currently no cure and half die within 14 months of being diagnosed. In the UK, there are about 5,000 people with the condition. Stephen Hawking, the 66-year-old Cambridge physicist, was diagnosed with a rare form of motor neurone disease 45 years ago. He is now almost completely paralysed, although, as with most other patients, his mind remains active.
Doctors are unsure precisely how lithium works, but its effectiveness as an anti-depression treatment is thought to be linked to its ability to slow down electrical activity in brain cells.
Doctors are now recruiting patients who experienced their first symptoms of the disease within the past six months to three years. Results from the trial are expected within two years. It will be considered a success if patients who are given the drug live 20% longer than those who receive a placebo(安慰剂). "It would be very nice if we show lithium arrests the disease but we’re not expecting that. We’re hoping for a three- to six-month increase in lifespan over the 18-month trial," said Leigh.
If the drug is effective, it could be given to thousands of patients immediately. But doctors advised patients against taking it until the trial was over. Taken unsupervised, it could put them at risk of side-effects including confusion, kidney failure and damage to the thyroid gland(甲状腺), they warned. [br] What kind of patients are the British doctors recruiting into their trial?
选项
A、Those who are in the early stage of the motor neurone disease.
B、Those who are in the late stage of the motor neurone disease.
C、Those who are in the early stage of the depression.
D、Those who are in the late stage of the depression.
答案
A
解析
本题解题的关键在于找到原文该句中的the disease指的是运动神经元疾病还是抑郁症,虽然上一段提到了depression,但从第7段的内容,特别是第3句提到的关于寿命的延长的内容,可以推断本段中的医生要研究的是运动神经元疾病。该段首句提到的first symptoms表明医生需要处于患病初期的病人参与试验。将这两点结合起来,可确定A为正确答案。
转载请注明原文地址:https://tihaiku.com/zcyy/2925818.html
相关试题推荐
Postgraduatedilemmas[A]Decidingwhetherornottobeco
Postgraduatedilemmas[A]Decidingwhetherornottobeco
Postgraduatedilemmas[A]Decidingwhetherornottobeco
[originaltext]Everyyear,itcostsBritishstudentsmoreandmoretoattend
Britishdoctorsaretolaunchamajorclinicaltrialtoinvestigatewhether
Britishdoctorsaretolaunchamajorclinicaltrialtoinvestigatewhether
Britishdoctorsaretolaunchamajorclinicaltrialtoinvestigatewhether
[originaltext]SpeakingattheBritishScienceFestivalonTuesday,ProfKel
[originaltext]SpeakingattheBritishScienceFestivalonTuesday,ProfKel
[originaltext]You’veprobablyseenencyclopedias.Whetheryou’resettlinga
随机试题
Thedancersstandmotionlessattheirpositionandtheroomgrowssilent.Bu
Peopletendtobemoreimpressedbyevidencethatseemstoconfirmsomerela
Peopleshouldwear______dresstheyfeelcomfortablein.A、whatB、thatC、whichD
[originaltext]M:Idolikethosecolorfulbirds.Ithinkyoucanteachthemto
创业投资企业存续期限最短不得短于( )年。A.2 B.3 C.5 D.7
地脚螺栓对安装精度的影响主要是()。A、地脚螺栓紧固力不够 B、地脚螺栓中心线
根据下列统计资料回答问题。 2009年世界天然气贸易量达8768.5亿立方米
商业银行应当明确个人理财业务人员与一般产品和服务人员的工作范围界限,禁止一般产品
2020年4月张某作为人才被引入某公司,该公司将购置价800000元的
1999年,国际货币基金组织按照汇率弹性从小到大,将汇率制度分为多种,其中汇率弹
最新回复
(
0
)