首页
登录
职称英语
British doctors are to launch a major clinical trial to investigate whether
British doctors are to launch a major clinical trial to investigate whether
游客
2023-08-18
31
管理
问题
British doctors are to launch a major clinical trial to investigate whether a common anti-depression drug could be a cheap and effective treatment for the destructive condition motor neurone(运动神经元)disease.
The trial, which is due to start in January, will follow more than 200 patients with motor neurone disease over 18 months to see if those given daily lithium pills live longer. Lithium is already licensed for treating depression and other mental disorders, and is extremely cheap, costing just 48p for a packet of 20 pills.
The £1m trial follows the publication in February of a small study by Italian researchers which suggested that lithium could slow the progression of the disease dramatically. The study sparked a surge of interest in the drug among online patient groups, and some doctors now offer lithium "off-label", despite widespread uncertainty as to whether it works.
Nigel Leigh, director of the motor neurone disease care centre at King’s College London, who will lead the trial, said: "It is our responsibility and duty to carry out this trial because we have to consider every lead seriously, and where there is real uncertainty, resolve it swiftly. The results of the Italian trial are too dramatic to ignore."
Motor neurone disease destroys nerves in the brain that control movement, leaving patients locked in a failing body. There is currently no cure and half die within 14 months of being diagnosed. In the UK, there are about 5,000 people with the condition. Stephen Hawking, the 66-year-old Cambridge physicist, was diagnosed with a rare form of motor neurone disease 45 years ago. He is now almost completely paralysed, although, as with most other patients, his mind remains active.
Doctors are unsure precisely how lithium works, but its effectiveness as an anti-depression treatment is thought to be linked to its ability to slow down electrical activity in brain cells.
Doctors are now recruiting patients who experienced their first symptoms of the disease within the past six months to three years. Results from the trial are expected within two years. It will be considered a success if patients who are given the drug live 20% longer than those who receive a placebo(安慰剂). "It would be very nice if we show lithium arrests the disease but we’re not expecting that. We’re hoping for a three- to six-month increase in lifespan over the 18-month trial," said Leigh.
If the drug is effective, it could be given to thousands of patients immediately. But doctors advised patients against taking it until the trial was over. Taken unsupervised, it could put them at risk of side-effects including confusion, kidney failure and damage to the thyroid gland(甲状腺), they warned. [br] According to Nigel Leigh, the results of the Italian trial are _____.
选项
A、noteworthy
B、unreliable
C、doubtless
D、insignificant
答案
A
解析
原文该句中的too…to ignore表明意大利的实验结果“不容忽视”,那也就是说,他们的实验结果值得关注,本题应选A。
转载请注明原文地址:https://tihaiku.com/zcyy/2935655.html
相关试题推荐
[originaltext]M:IwaswonderingwhetherIshouldchooseanITmajorincompute
[originaltext]M:IwaswonderingwhetherIshouldchooseanITmajorincompute
[originaltext]M:IwaswonderingwhetherIshouldchooseanITmajorincompute
[originaltext]M:IwaswonderingwhetherIshouldchooseanITmajorincompute
[originaltext]M:IwaswonderingwhetherIshouldchooseanITmajorincompute
[originaltext]M:IwaswonderingwhetherIshouldchooseanITmajorincompute
[originaltext]Abloodtestthatcanpredictwhethersomeonemayattemptsui
[originaltext]Abloodtestthatcanpredictwhethersomeonemayattemptsui
IntheBritishMuseumonaSundayafternoon,ancientfaceslookbackatchil
IntheBritishMuseumonaSundayafternoon,ancientfaceslookbackatchil
随机试题
"Don’tforget(take)______allyourluggagewithyouwhenyouleavethehotel."
Therearesome______flowersonthetable.A、artificialB、unnaturalC、假D、unrealA
A
出口车道主要设备有(),A.车道控制器 B.读写卡机 C.费额显示器 D
机器设备的清查核实,是确定机器设备是否存在、明确机器设备的存在状态并对其法律权属
患者,女性,59岁。持续高热3天,每隔4小时测一次体温,都在39.1℃以上,最高
对急性粒细胞性白血病有肯定价值的细胞化学染色是A.过氧化物酶染色B.过碘酸-雪夫
当气温低于( )时,不得对混凝土洒水养护。 A、0℃ B、-5℃ C
饮在肠间可见A.腹满 B.肠鸣沥沥有声 C.食少 D.大便稀溏
(2019年真题)关于预约定价安排的管理和监控,下列说法正确的是()。A.预约
最新回复
(
0
)