首页
登录
职称英语
Sleep deprivation is a quick and efficient way to treat depression. It works
Sleep deprivation is a quick and efficient way to treat depression. It works
游客
2025-03-29
11
管理
问题
Sleep deprivation is a quick and efficient way to treat depression. It works 60 to 70 percent of the time — far better than existing drugs — but the mood boost usually lasts only until the patient falls asleep. As an ongoing treatment, sleep deprivation is impractical, but researchers have been studying the phenomenon in an effort to uncover the cellular mechanisms behind depression and
remission
. Now a team at Tufts University has pinpointed glia as the key players.
The researchers previously found that astrocytes, a star-shaped type of glial cell, regulate the brain chemicals involved in sleepiness. During our waking hours, astrocytes continuously release the neurotransmitter adenosine, which builds up in the brain and causes " sleep pressure," the feeling of sleepiness and its related memory and attention impairments. The neurotransmitter causes this pressure by binding to adenosine receptors on the outside of neurons like a key fitting into a lock. As more adenosine builds up, more receptors are triggered, and the urge to sleep gets stronger.
In the new study, published online January 15 in the journal Translational Psychiatry, the scientists investigated whether this process is responsible for the antidepressant effects of sleep deprivation. Mice with depressive-like symptoms were administered three doses of a compound that triggers adenosine receptors, thus mimicking sleep deprivation. Although the mice continued to sleep normally, after 12 hours they showed a rapid improvement in mood and behavior, which lasted for 48 hours.
The results confirm that the adenosine buildup is responsible for the antidepressant effects of a lack of sleep. This finding points to a promising target for new drug development because it suggests that mimicking sleep deprivation chemically may offer the antidepressant benefits without the unwanted side effects of actually skipping sleep. Such an intervention could offer immediate relief from depression, in stark contrast with traditional antidepressants, which take six to eight weeks to kick in.
The study may also have implications beyond depression and sleep regulation, according to Dustin Hines, lead author and a postdoctoral fellow at Tufts. " For many years, neuroscientists focused almost exclusively on neurons, whereas the role of glia was neglected," Hines says. "We now know that glia play an important role in the control of brain function and have the potential to aid in the development of new treatments for many illnesses, including depression and sleep disorders." [br] What does the underlined word "remission" in Para. 1 probably mean?
选项
A、Lessening of depression.
B、Recurrence of depression.
C、Recovery from depression.
D、Medication for depression.
答案
A
解析
本题是词汇题,要求考生能够从上下文的主要语义大致推断出词汇的意思。文章第一段中提到睡眠缺乏症可以缓解抑郁症,例如上文提到的“60%—70%”这一信息表明起到了缓解作用,而不是彻底治疗。
转载请注明原文地址:https://tihaiku.com/zcyy/4017409.html
相关试题推荐
Sleepdeprivationisaquickandefficientwaytotreatdepression.Itworks
Sleepdeprivationisaquickandefficientwaytotreatdepression.Itworks
Sleepdeprivationisaquickandefficientwaytotreatdepression.Itworks
Sleepdeprivationisaquickandefficientwaytotreatdepression.Itworks
Sleepdeprivationisaquickandefficientwaytotreatdepression.Itworks
Sleepdeprivationisaquickandefficientwaytotreatdepression.Itworks
随机试题
TheearlyretirementofexperiencedworkersisseriouslyharmingtheU.S.e
Formostpeople,keepingfitinvolvesanestablishedexerciseroutinebuilta
某男性工人,在东北某森林地区从事野外伐木工作,工龄5年,近来常感手部疼痛、麻木,
根据《宪法》规定,关于国务院的说法,下列选项正确的是()。A.国务院由总理、副
黄连解毒汤中黄芩的作用是A.清中焦火邪 B.清三焦火邪 C.清中上焦火邪
财务预测的审查包括()。 A.成本、利润的审查B.销售收入审查 C.税金
可摘义齿,导致面部酸痛的原因和咀嚼无力的原因是( )。A.咀嚼肌疾患 B.垂
陈某因涉嫌盗窃罪被起诉至某县人民法院。在休庭时,陈某趁看守不注意,越窗逃走,致使
下列建设工程施工合同无效情况下产生的价款纠纷,法院不予支持的是()。A.工
男性,70岁。高血压性心脏病史10年,1月来出现夜间阵发性呼吸困难,1天来气喘、
最新回复
(
0
)