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What did a panel of cancer experts rule concerning the cancer drug Avastin? [br]
What did a panel of cancer experts rule concerning the cancer drug Avastin? [br]
游客
2024-12-22
20
管理
问题
What did a panel of cancer experts rule concerning the cancer drug Avastin? [br]
A panel of cancer experts ruled Wednesday that Avastin—the world’s best-selling cancer drug, developed by Genentech in South San Francisco—should no longer be used in breast cancer patients because of concerns that the medicine didn’t work as well in follow-up studies and may cause deadly bleeding.
Outside advisers to the Food and Drug Administration voted 6-0 against Avastin’s use in breast cancer at a hearing. Their recommendations will be sent to FDA Commissioner Margaret Hamburg, who will make the final ruling on. Avastin will remain on the market because it’s approved for four other types of tumors—lung, kidney, colon and brain cancer. Approval for those uses won’t be affected by Wednesday’s recommendation.
The FDA gave Avastin accelerated approval for breast cancer in February 2008 on the basis of one study that suggested the medicine, combined with chemotherapy, slowed tumor growth by 5 1/2 months. Required follow-up tests found Avastin kept cancer at bay for one to two months. (8) The drug was also tied to more life-threatening side effects such as severe bleeding, stomach tears and high blood pressure.
San Francisco Chronicle
选项
A、Deadly bleeding.
B、Stomach tears.
C、Kidney failure.
D、High blood pressure.
答案
C
解析
细节题。新闻中提到的Avastin对乳腺癌病人造成的致命副作用除严重出血外,还包括:严重出血、胃部撕裂和高血压:The drug was also tied to more life-threatening side effects such as severe bleeding,stomach tears and high blood pressure。因此答案为C。
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