首页
登录
职称英语
A team of international researchers has found new evidence that an endangere
A team of international researchers has found new evidence that an endangere
游客
2023-12-14
35
管理
问题
A team of international researchers has found new evidence that an endangered subspecies of chimpanzee is the source of the virus that causes acquired immune deficiency syndrome (AIDS) in humans. Experts said the finding could lead to new treatments for AIDS and contribute to the development of a vaccine against the disease.
The research team said the chimp -- a subspecies known as Pan troglodytes troglodytes native to west central Africa -- carries a simian immunodeficiency virus (SIV) that is closely related to three strains of human immunodeficiency virus ( HIV), the virus that causes AIDS. One of these strains, HIV - 1, has caused the vast majority of the estimated 30 million HIV infections around the world.
The researchers are uncertain when the chimp virus, called SIVcpz (for simian immunodeficiency virus chimpanzee), first infected humans, although the oldest documented case of HIV has been linked to a Bantu man who died in Central Africa in 1959. But they said the virus, which does not appear to harm the chimps, was most likely transmitted to humans when hunters were exposed to chimp blood while killing and butchering the animals for food. Once transmitted to humans, the researchers believe the virus mutated into HIV -1.
Team leader Beatrice Hahn, an AIDS researcher at the University of Alabama in Birmingham, said the chimps have probably carried the virus for hundreds of thousands of years. Since humans have likely hunted the animals since prehistoric times, Hahn said the virus may have jumped to humans on many occasions, but was not trans, nined widely among humans until the 20th century.. Increased hunting of the chimpanzees, along with human migration to African cities and changing sexual mores, could help explain the recent epidemixc, Hahn said.
Scientists had long suspected that a nonhuman primate was the source of HIV - 1. Earlier studies suggested that the sooty mangabey monkey, a native of West Africa, was the likely source of HIV - 2 -- a rarer torm of the AIDS virus that is transmitted less easily than HIV - 1. However, only a few samples of SIV strains exist, making it difficult for researehers to confidently connect the strains to HIV - 1.
As part of their effort to discover the source of HIV - 1, the research team studied the four known samples of SIVcpz. They learned that three of the four samples came from chimps belonging to the subspecies P.t. troglodytes. The remaining sample came from another subspecies, Pan troglodytes schweinfurthii, which inhabits East Africa.
The team then compared the SIVcpz strains to each other and found that all three of the viruses from P. t. troglodytes were closely related, while the virus from P.t. schweinfurthii was genetically different. Next they compared the SIVepz strains to the main subgroups of HIV - 1, known as M, N, and O. Their comparisons showed that the P.t. troglodytes viruses strongly resembled "all three HIV -1 subgroups.
Additional evidence that HIV - 1 could be linked to P. t. troglodytes came when the researchers examined the chimps’ natural habitat. The researchers quickly discovered that the chimps live primarily in the West African nations of Cameroon, Central African Republic, Gabon, Equatorial Guinea, and Republic of the Congo the geographic region where HIV - 1 was first identified.
Upon closer study, the researchers learned that the chimps were being killed in growing numbers for the so - called bush meat trade, a trend assisted by the construction of new logging roads in once remote forests. The researchers said that continued hunting of the animals meant that many people are still likely to be exposed to SIVepz, increasing the risk of additional cross - species transmissions.
Many AIDS researchers welcomed the team’s finding, but said the new work had not proved the connection definitively. Most of the doubts centered on the difficulty of drawing conclusions from such a small number of SIVepz samples. Because so few samples exist -- all drawn from chimps in captivity -- researchers do not know how prevalent the virus is among wild chimps, or how the virus is transmitted. Doubts are likely to persist until the course of the virus is studied in chimps in the wild.
Some health experts said the finding could have far- reaching implications for combating AIDS. Because SIVepz does not cause the chimps to become ill, researchers believe that the animals’ disease - fighting immune systems may have developed a defense against the virus. Since chimps are 98 percent genetically similar to humans, learning more about the chimps’ immune systems could shed light on new ways to prevent and treat AIDS in humans. Discovering how the chimp’s immune system controls the virus, for example, could help researchers develop a vaccine that generates a similar immune -system response in humans.
Other experts noted that even if the finding does not help in the fight against AIDS, it provides strong evidence that dangerous viruses can be transmitted to humans from wild animals, in some cases, the viruses may be harmless to the host animals, but cause sickness and death when transmitted to humans. As people increasingly venture into remote animal habitats, some scientists believe there is a growing risk of new human exposures to previously unknown disease- causing microbes.
In the meantime, widespread slaughter of the chimps could make further study of P. t. troglodytes difficult. The wild chimp population, which exceeded 1 million animals in the early 20th century, is now believed to number fewer than 100,000. "We cannot afford to lose these animals, either from the animal’s conservation point of view or a medical investigation standpoint," said Hahn. "It is quite possible that the chimpanzee, which has served as the source of HIV - 1, also holds the clues to its successful control. " [br] The biggest worry that the researchers now have is ______.
选项
A、more and more wild chimpanzees are being slaughtered
B、AIDS virus is difficult to be killed and controlled
C、it is not easy to repair people’s deficient immune systems
D、many dangerous viruses are being transmitted to humans
答案
A
解析
文章最后一段提到使问题更困难的是对黑猩猩的屠杀,使其数量急剧减少。
转载请注明原文地址:https://tihaiku.com/zcyy/3272049.html
相关试题推荐
Beguninthelate1960sbyPentagonweaponsresearchersasasystemforeasing
Beguninthelate1960sbyPentagonweaponsresearchersasasystemforeasing
Beguninthelate1960sbyPentagonweaponsresearchersasasystemforeasing
Beguninthelate1960sbyPentagonweaponsresearchersasasystemforeasing
Beguninthelate1960sbyPentagonweaponsresearchersasasystemforeasing
SevenTypesofEvidenceItisimportanttolearntouseevidencein
SevenTypesofEvidenceItisimportanttolearntouseevidencein
SevenTypesofEvidenceItisimportanttolearntouseevidencein
SevenTypesofEvidenceItisimportanttolearntouseevidencein
SevenTypesofEvidenceItisimportanttolearntouseevidencein
随机试题
Makesureyourheadsetison.TheWritingsectionmeasuresyourability
Belowaretwoexcerptsonanimportantconcernofmusicindustry:whetherit
图示矩形截面梁,高度h=120mm,跨度l=1m,梁中点受集中力P,两端受拉力
A. B. C. D.
安全生产知识考核内容包括建筑施工安全的()等。A.法律法规 B.规章制度
在进行软件开发时,采用无主程序员的开发小组,成员之间相互平等;而主程序员负责制的
某上市公司目前总资产10000万元,其中股东权益4000万元,普通股股数3500
根据内幕消息买卖某上市公司股票,但是交易却造成损失的行为不属于内幕交易行为。(
下列关于退休年龄的说法,错误的是()。A.男满60周岁 B.女工人满55
阀控式密封铅酸蓄电池在使用前,若低于2.13v或储存期达3-6个月,应运用()进
最新回复
(
0
)