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Many who think they have food allergies(过敏)actually do not. A new report, co
Many who think they have food allergies(过敏)actually do not. A new report, co
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2023-08-13
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问题
Many who think they have food allergies(过敏)actually do not. A new report, commissioned by the federal government, finds the field is full of poorly done studies, misdiagnoses and tests that can give misleading results.
While there is no doubt that people can be allergic to certain foods, the true incidence of food allergies is only about 8 percent for children and less than 5 percent for adults, said Dr. Marc Riedl, an author of the new paper and an allergist and immunologist at the University of California, Los Angeles.
Yet about 30 percent of the population believe they have food allergies. And, Dr. Riedl said, about half the patients coming to his clinic because they had been told they had a food allergy did not really have one. Dr. Riedl does not dismiss the seriousness of some people’s responses to foods. But, he says, "That accounts for a small percentage of what people term ’food allergies.’ " Even people who had food allergies as children may not have them as adults. People often shed allergies, though no one knows why. And sometimes people develop food allergies as adults, again for unknown reasons.
For their report, Dr. Riedl and his colleagues reviewed all the papers they could find on food allergies-more than 12,000 articles. In the end, only 72 met their criteria, which included having sufficient data for analysis and using more rigorous tests for allergic responses.
"Everyone has a different definition" of a food allergy, said Dr. Jennifer J. Schneider Chafen, the lead author of the new report. People who receive a diagnosis after one of the two tests most often used— piercing the skin and injecting a tiny amount of the suspect food and looking in blood for IgE antibodies(抗体), the type associated with allergies—have less than a 50 percent chance of actually having a food allergy, the investigators found.
One way to see such a reaction is with what is called a food challenge, giving people a suspect food disguised so they do not know if they are eating it or a placebo(安慰剂)food. If the disguised food causes a reaction, the person has an allergy.
But in practice, most doctors are reluctant to use food challenges, Dr. Riedl said. They believe the test to be time consuming, and worry about asking people to consume a food, like peanuts, that can elicit a frightening response.
The paper, to be published Wednesday in The Journal of the American Medical Association, is part of a large project organized by the National Institute of Allergy and Infectious Diseases to try to impose order on the chaos of food allergy testing. An expert panel will provide guidelines defining food allergies and giving criteria to diagnose and manage patients. They hope to have a final draft by the end of June. [br] The IgE antibodies are produced when______.
选项
A、the skin is pierced
B、the suspect food is injected
C、there is an allergic reaction
D、there is a diagnosis
答案
C
解析
该句中the type associated with allergies是对IgE antibodies的进一步解释。可见,IgE这种抗体与过敏症有关,这也就是说,当人体发生过敏反应时,就会产生IgE抗体。因此,本题应选C。
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