首页
登录
职称英语
Modern offices may scorn the stuff, but paper has found a new use in the lab
Modern offices may scorn the stuff, but paper has found a new use in the lab
游客
2023-07-19
51
管理
问题
Modern offices may scorn the stuff, but paper has found a new use in the laboratory — as the basis for 3D models of tumours and damaged hearts.
Chemist George Whitesides and his colleagues at Harvard University reckon that the balls of cells they have grown at the centre of stacked paper could help us better understand how tumours and damaged hearts respond to drugs, and even to select therapies most suited to individuals.
Cells tend to be grown on flat plates in the lab, which isn’t representative of the 3D structure of cells in the body. "It’s nothing like human tissue," says Whitesides. In our bodies, cells are exposed to natural concentration gradients: the further away they are from major blood vessels, the less oxygen and nutrients they get. But in 2D cell cultures, such gradients aren’t present. "We need to move away from those boring flatlands that cell culture dishes represent," says cell biologist Emmanuel Reynaud who was not involved in the research.
Although techniques for growing cells in 3D exist, many are time-consuming and far from perfect. For example, once the cells have grown, the cultures need to be sliced with a knife to be analysed. "Not only does this kill some cells, it’s extremely difficult to do," Whitesides says. His group has now developed a cheap alternative.
The team start by spraying a gel containing their cells onto small sheets of sterile chromatography paper (无菌色谱纸). The cells they used included human lung cancer cells, human fibroblasts (纤维原细胞), which make up connective tissue, and mouse immune cells. "I tried everything I could get my hands on," says Whitesides.
The cells seeped through the paper "like coffee through a napkin (餐巾)", he says. When the researchers stacked up eight sheets of cell-infused paper and suspended them in an oxygen and nutrient-rich broth (液体培养基), they found that the cells grew into a ball.
To analyse how these cells behaved, the researchers simply peeled off the layers one at a time and analysed them individually. It seemed that the outer cells closer to the medium were nourished while the cells on the inside showed signs of being starved, which is what you would expect to happen to a tumour inside the body. [br] What can we know about the benefit of the new use of paper from the passage?
选项
A、It can save more resources used in the research.
B、It enables researchers to do experiments on 3D models.
C、It’s helpful for doctors to study patients’ tumors and damaged hearts.
D、It’s useful for doctors to select the most suitable treatment for patients.
答案
C
解析
文章在第一段最后提到纸的新用途是在实验室作为肿瘤及受损心脏3D模型的基础,第二段最后又提到纸堆中间的那些细胞团有助于更好地了解肿瘤及受损心脏对药物的反应,由此可知答案为[C]。[D]是了解肿瘤和受损心脏对药物的反应后要做的,故可排除。[A]、[B]文中未提到。
转载请注明原文地址:https://tihaiku.com/zcyy/2851499.html
相关试题推荐
Themodernworldcouldnotoperatewithoutroads.Itisawayoflifewith
Themodernworldcouldnotoperatewithoutroads.Itisawayoflifewith
Themodernworldcouldnotoperatewithoutroads.Itisawayoflifewith
Themodernworldcouldnotoperatewithoutroads.Itisawayoflifewith
Themodernworldcouldnotoperatewithoutroads.Itisawayoflifewith
Themodernworldcouldnotoperatewithoutroads.Itisawayoflifewith
Modernmedicaladvances______theaveragelifeexpectancybyseveralyears.A、ex
Theirliveswerenow______byearthshakingchange,bythearrivalofthemodern
[originaltext]CocaColaCo.,oftenviewedasasymbolofmodernAmericancultur
[originaltext]CocaColaCo.,oftenviewedasasymbolofmodernAmericancultur
随机试题
Theman’sefforttofindapositiondoesnotinclude_____.[originaltext]M:Id
Anovertimpactofmodeminformationsystemsconcernstheindividual’sstanda
WhichofthefollowingdetailsaboutthenewsisINCORRECT?[originaltext]Fe
CultureShockA)BecauseI’velivedinChinaforalongtime,localsoft
集中火灾报警控制器、消防联动控制器、消防控制室图形显示装置,外壳外观保养的保养方
在对竖直桩进行机械钻孔倾斜度检测时,当检测结果不超过桩长的()时,满足使用
女,产后出现单纯性外痔。其主要表现为A、出血 B、肛门部剧烈疼痛 C、肛门失
对急性胰腺炎的治疗下列哪种措施不恰当? A.持续胃肠减压B.补充钙剂C.给
DNA分子较RNA分子在化学结构上更为稳定的原因是 A.两者所含碱基不同B.
目前国际上应用比较广泛的信用风险组合模型包括()。A.CreditMetric
最新回复
(
0
)