首页
登录
职称英语
Growing concerns over the safety and efficacy of anti-depressant drugs presc
Growing concerns over the safety and efficacy of anti-depressant drugs presc
游客
2023-12-15
46
管理
问题
Growing concerns over the safety and efficacy of anti-depressant drugs prescribed to children have caught the eye of Congress and the New York state attorney general. Now they’re becoming the catalyst for calls to reform the way clinical trials of all drugs are reported.
Pressure is already causing some changes within the pharmaceutical industry. And it has put the US Food and Drug Administration (FDA), which approves new drugs, in the hot seat. If reforms are carried out, they could bring an unprecedented level of transparency to drug research.
The solution now under consideration: a public database, or registry, of drug trials, where companies would post the results of those trials.
In congressional testimony Thursday, a spokesman for the American Medical Association endorsed the registry and said it should include information on each trial’s purpose and objective, its design, and the dates it begins and ends. If the trial is not completed, the registry should include an explanation.
While drug companies have been eager to make public any positive results of their trials, recent revelations suggest they’ve balked at divulging tests when the results are not what they’d hoped to see. The furor has centered around the use Of anti-depressants on children.
The industry has begun to make some moves to address the concerns about drug trials. Drug companies have agreed to set up a voluntary system of posting their drug trials on the Internet. But that seems unlikely to satisfy some members of Congress, who are expected to introduce legislation to establish a mandatory drug registry.
Last week, editors of a dozen influential medical journals announced that they would begin requiring drug companies to post a drug trial in a public database prior to accepting an article about it. Doctors rely on these articles to make treatment choices. The editors hope that the registry will force unfavorable drug studies, before kept secret, into the open.
Medical journals already had been tightening up on the authorship of their articles, insisting that authors declare if they had any conflicts of interest, such as any financial or other ties to the drug company, says Daniel Callahan, a director at the Hastings Center, a nonprofit bioethics research institute in Garrison, N.Y.
Information from previously undisclosed clinical trials could lower prices, reduce the number of badly designed trials, and help doctors considering the use of a drug for a non-approved purpose to know why it hasn’t been approved for that use.
Antidepressant drugs "have some serious side effects ... that seem to be much more common than people realize ... much more common than you might think from seeing drug ads and from reports on drug studies," says Joel Gurin, executive vice president of Consumer Reports. His magazine just finished a survey of readers showing a "dramatic shift from talk therapy to drug therapy for mental health problems" during the past decade. In 1995, less than half of people getting mental health treatment--40 percent--got drug therapy. Today 68 percent receive drug treatment, Mr. Gurin says.
Some studies coming to light show that antidepressants work no better than placebos. Even better than merely registering drug trials, Caplan (director of the Center for Bioethics at the University of Pennsylvania in Philadelphia) suggests, would be to require that a new drug not only be "safe and do what it’s supposed to do", but that it do it as well or better than other drugs already on the market. That, he says, would help push research into new areas and save money. [br] What is Caplan’s opinion in the last paragraph?
选项
A、Registry of drug trials is of no use.
B、We should make demands on new drugs besides registering drug trials.
C、To put requirements on new drugs is much more effective than registering drug trials.
D、A new drug must be safe and better than any other drugs already on the market.
答案
B
解析
最后一段中Caplan的观点是什么?caplan指出“Even better than merely registering…”,“merely”这个词暗示,说话者意思是不仅要登记药品临床试验结果还要保证新药品安全并至少和市场上现有的药品一样有效。
转载请注明原文地址:http://tihaiku.com/zcyy/3275581.html
相关试题推荐
Growingconcernsoverthesafetyandefficacyofanti-depressantdrugspresc
WhichofthefollowingisTRUEaboutthesafetyofputtingphotosonline?[br]
WhichofthefollowingisTRUEaboutthesafetyofputtingphotosonline?[br]
WhichofthefollowingisTRUEaboutthesafetyofputtingphotosonline?[br]
WhichofthefollowingisTRUEaboutthesafetyofputtingphotosonline?[origi
WeliveinsouthernCaliforniagrowinggrapes,afirstgenerationofvintner
WeliveinsouthernCaliforniagrowinggrapes,afirstgenerationofvintner
WeliveinsouthernCaliforniagrowinggrapes,afirstgenerationofvintner
WeliveinsouthernCaliforniagrowinggrapes,afirstgenerationofvintners
WeliveinsouthernCaliforniagrowinggrapes,afirstgenerationofvintners
随机试题
[img]2017m2x/ct_ehbm_ehbreadf_0047_201702[/img][br]Sneezedropletscouldhang
Thelaptopcomputerisasmall,portab
下列预算表格中,( )是编制劳动力计划、合理调配劳动力的依据。A.施工预算工料
一般中药的常用内服剂量是A.5~10g B.10~15g C.10~3
双侧瞳孔不等大见于()。A.视神经萎缩 B.吗啡中毒 C.阿托品中毒 D
247、加强带电显示()的运行维护,保证其与柜门间强制闭锁的运行可靠性。防误
(2021年上半年真题)在课堂教学中,文老师不仅能够深入浅出地讲解学科知识,而且
某建筑高度为38m,且设有消防电梯的五层针织品生产厂房,耐火等级为一级,每层建筑
资产负债表日,企业对未来现金流量为外币的固定资产进行减值测试时,应当以资产负债表
某工程钢筋混凝土基础底板,长度120m,宽度100m,厚度2.0m。混凝土设计强
最新回复
(
0
)