首页
登录
职称英语
The first step to defeat an enemy is to pin down his exact identity and how
The first step to defeat an enemy is to pin down his exact identity and how
游客
2023-08-29
47
管理
问题
The first step to defeat an enemy is to pin down his exact identity and how he operates. Hypertension — chronic, abnormally raised blood pressure — causes heart attacks, strokes and a multitude of other nasty conditions. Around a third of Americans and Britons suffer from it. It is thus a worthy enemy and nailing its cause is a priority. Until now, this has mostly seemed to lie in the kidneys. But Hidefumi Waki and Julian Paton of Bristol University think they have gathered some valuable new intelligence by studying the brain.
In a previous experiment Dr Waki and Dr Paton had found that rodents(啮齿动物)with high blood pressure expressed some genes differently in an area of the brain, called the solitary nucleus(孤束核, which sets the body’s normal blood-pressure level. One of these genes was called "junctional adhesionmolecule-1" or JAM-1 for short. It is a molecule normally found in the walls of blood vessels that attracts clotting and immune cells — in other words, it causes inflammation(炎症). So the pair decided to look at JAM-1 in further depth.
They found that in rats with high blood pressure JAM-1 levels were raised not only in the brain but also the kidney, lungs and skeletal muscle. To find out whether this was the cause or effect of high blood pressure, they then transferred the JAM-1 gene into the solitary nucleus of normal rats. After two weeks, these rats suffered from higher blood pressure than rats that had not received the gene.
Previously, experts thought that high blood pressure was caused by the kidneys. The idea was that the kidneys failed to sense the blood pressure. This then caused the lungs to make a hormone that increases blood pressure, leading to a chain of events that raised pressure throughout the blood-vessel network. All blood-pressure-lowering drugs work by seeking to put this right. Yet blaming the kidneys cannot be the full explanation of what is going on, because only half the sufferers respond to blood-pressure-lowering drugs.
Although these findings are preliminary, they have far-reaching implications. Variations in the JAM-1 gene and its expression may explain why high blood pressure tends to run in families, although it is also caused by a poor diet. The finding also shows that the brain could increase the activity of the sympathetic nerves, the part of the nervous system involved in stress response. Ultimately, the finding could hasten the development of drugs that would attack hypertension at its source, stopping its deadly consequences in their tracks. [br] What were the previous drugs intended to do to lower high blood pressure?
选项
答案
To help the kidney sense the blood pressure
解析
由线索词previous drugs定位至第四段倒数第二句,文中说所有的降压药都是通过使肾脏恢复感知血压的功能而产生效用的。关键是理解put this right的含义。据此,可以将答案改写为Tohelp the kidney sense the blood pressure。
转载请注明原文地址:http://tihaiku.com/zcyy/2967489.html
相关试题推荐
Proofofidentityisrequiredfor______(在大多数银行兑现支票).cashingacheckatmostb
【B1】[br]【B2】A、succeedB、enrichC、winD、defeatA前文说赌徒追逐金钱,结果却把钱输了,接着进行转折:但其他生财的
Thefirststeptodefeatanenemyistopindownhisexactidentityandhow
Thefirststeptodefeatanenemyistopindownhisexactidentityandhow
Thefirststeptodefeatanenemyistopindownhisexactidentityandhow
Thefirststeptodefeatanenemyistopindownhisexactidentityandhow
Thefirststeptodefeatanenemyistopindownhisexactidentityandhow
随机试题
[originaltext]Anewstudyonclimatechangesaysadisastrous4-degreerise
汉语热指近年来越来越多的外国人开始学习汉语的现象。在很多国家。学汉语的人数在迅速增长。据统计。全世界已有109个国家、3000多所高等学校开设了汉语课程
[originaltext]W:Youlookverysleepyandtired.What’swrong,John?Didyoust
ThemainstepsofITstrategicplanning
随着科学技术的发展,信息技术已经逐渐融入人们的日常生活。下列表述正确的是()。
下列有关药物表观分布容积的叙述中,正确的是A.表观分布容积大,表明药物在血浆中浓
根据以下资料,回答问题。2011年我国城乡居民人均文化消费比2002年分别增长1
右心衰竭时,发生组织水肿的原因是A.血管胶体渗透压降低 B.毛细血管通透性增高
以下关于远期和期货的说法,正确的有()。A.远期合约是标准化的 B.期货合约
下列疾病的直接病因是 增生性龈炎A.牙菌斑 B.服用药物 C.内分泌导致的
最新回复
(
0
)