In last year’ s Science study, researchers at Johns Hopkins University exami

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问题 In last year’ s Science study, researchers at Johns Hopkins University examined the relationship between stem-cell divisions and cancer development. They reported that the higher the number of stem-cell divisions in a given tissue, the higher risk for【C1】______cancer. At the time, they said that their findings suggested "65% of cancer... appears to be explained by the number of stem-cell divisions". That stem-cell activity, the researchers suggested, could explain why some people without【C2】______factors like smoking will still get lung cancers.
" I was startled by their conclusion," Dr. Yusuf Hannun says, a cancer researcher at Stony Brook University in New York and author of the new Nature study. Hannun and his team【C3】______that the first study assumed that stem-cell division and other environmental factors were【C4】______of each other.
Hannun’ s team wanted to assess the【C5】______to which stem-cell division or environmental factors contribute to developing the disease. To do this, the researchers looked at a variety of data including epidemiological evidence that people living in different regions have different rates of cancer development. They also looked at cell-mutation patterns【C6】______with certain cancers, as well as mathematical models that helped parse how much a cancer was due to【C7】______factors like cell division versus extrinsic factors like environment or lifestyle.
The new study reported that while intrinsic factors did have a【C8】______in cancer development, environmental factors had a more【C9】______effect and were responsible for 70% -90% of cancer cases.
This isn’ t the last study to be published on the topic, but as scientists refine their【C10】______of the many things that can contribute to cancer risk, more information is needed.
A)argue I)intrinsic
B)associated J)relation
C)considering K)risk
D)derived L)robust
E)developing M)role
F)extent N)seizes
G)full O)understanding
H)independent [br] 【C2】

选项

答案 K

解析本空格前为without，空格后为名词factors，故本空格应该填一个名词或形容词。smoking应该是比较危险的致癌因素，故答案为K)risk(危险，风险)。

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