______so many difficulties, he didn’t give up his objection.A、Regardless ofB、In

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问题 ______so many difficulties, he didn’t give up his objection.

选项 A、Regardless of
B、In case of
C、In spite of
D、Despite of

答案 C

解析译文：尽管有那么多的困难，他依然没有放弃自己的目标。本题测试词组。regardless of意为“不管，不顾”；in case of意为“如果万一”；in spite of意为“尽管”；despite意为“尽管”，但它本身就是介词，后面不接of，所以C选项是正确答案。

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