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The evidence has gotten much stronger that a substance known as C-reactive p
The evidence has gotten much stronger that a substance known as C-reactive p
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2024-04-17
15
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The evidence has gotten much stronger that a substance known as C-reactive protein may be every bit as important as cholesterol(胆固醇)in the diagnosis and treatment of heart disease. Back in 2002, a thought-provoking study found that a blood test for C-reactive protein, called CRP, was actually better than the standard cholesterol test at predicting the risk of a heart attack or a stroke. Now two studies published in The New England Journal of Medicine have shown that drugs that reduce the levels of that protein in patients with severe heart disease can slow the progression of atherosclerosis(动脉硬化症)and prevent heart attacks and cardiac-related deaths.
Although the studies came laced with caveats, their cumulative impact suggests that cardiology is in the midst of a revolutionary shift in understanding the causes of heart disease. After years of focusing on the role of cholesterol in clogging arteries, researchers now recognize C-reactive protein, a measure of inflammation(炎症)in artery walls and elsewhere, as a prime risk factor in its own right.
The key study published last week found that heart disease patients who were given high doses of a cholesterol—lowering statin drug also experienced a drop in CRP levels and in heart attacks. Thus the high dose statin packed a double wallop.
These findings apply only to patients already suffering from severe heart disease. A separate clinical trial will seek to determine whether lowering C-reactive protein can reduce heart attacks in healthy patients with normal cholesterol levels but above-average levels of C-reactive protein. Nearly half of all people who suffer heart attacks have normal cholesterol levels, so it is critical to devise tests and treatments to reduce their risk.
Even before the final clinical results are in, it would seem prudent for all overweight couch potatoes who think they are safe because their cholesterol levels are low to get their C-reactive protein levels tested. If their CRP levels are high, they may be spurred to lose weight, exercise and stop smoking to bring down those protein levels. High doses of statins, with their risk of side effects, would presumably be a last resort. [br] The passage focuses on______.
选项
A、new findings about heart disease
B、causes of heart disease
C、treatment of heart disease
D、problems heart disease faces
答案
A
解析
本文讨论关于心脏病的研究发现:CRP的重要性,CRP是心脏病发病原因,发现降低CRP可减缓动脉硬化、预防心脏病发作及与心脏相关的疾病的死亡等。综上所述,本文重点讨论了关于心脏病的新发现,故A)正确。
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